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sirtuins-and-disease-the-road-ahead

TITLE : Sirtuins And Disease The Road Ahead

Sirtuins represent a promising new class of conserved histone deacetylases originally identified in yeast the activity of the sirtuin sirt family made up of seven members sirt1 7 is nad + dependentsirtuins represent a promising new class of conserved histone deacetylases originally identified in yeast the activity of the sirtuin sirt family made up of seven members sirt1 7 is nad+ dependent sirtuins target a wide range of cellular proteins in nucleus cytoplasm and mitochondria for post translational modification by we use cookies to make interactions with our website easy and meaningful to better understand the use of our services and to tailor advertisingintroduction epigenetic modifications play an important role in regulating gene expression lifespan and tumorigenesis in particular acetylation regulates a wide variety of cellular functionsabstract sirtuins represent a promising new class of conserved histone deacetylases originally identified in yeast the activity of the sirtuin sirt family made up of seven members sirt1 7 is nad+ dependent

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